Bradley W Wright, Dominic Y Logel, Mehdi Mirzai, Dana Pascovici, Mark P Molloy, and Paul R Jaschke. (2020). Proteomic and transcriptomic analysis of Microviridae φXI74 infection reveals broad up-regulation of host membrane damage and heat shock responses. bioRxiv. DOI: 10.1101/2020.10.26.355149
Abstract
Supplementary Information
Abstract
Supplementary Information
Bradley W Wright, Juanfang Ruan, Mark P Molloy, Paul R Jaschke. (2020). Genome modularization reveals overlapped gene topology is necessary for efficient viral reproduction. ACS Synthetic Biology. DOI: 10.1021/acssynbio.0c00323
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Bradley W Wright, Juanfang Ruan, Mark P Molloy, Paul R Jaschke. (2020). Genome modularization reveals overlapped gene topology is necessary for efficient viral reproduction. bioRxiv. DOI: 10.1101/2020.06.10.143693
Abstract Supplementary Information |
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Dominic Y Logel and Paul R Jaschke. (2020). A high-resolution map of bacteriophage ϕX174 transcription. Virology. 547: 47-56. DOI: 10.1016/j.virol.2020.05.008
Abstract
Abstract
Karen D. Weynberg and Paul R Jaschke. (2019). Building Better Bacteriophage with Biofoundries to Combat Antibiotic Resistant Bacteria. PHAGE: Therapy, Applications, Research. Accepted 30 Sept 2019. DOI: https://doi.org/10.1089/phage.2019.0005
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Paul R Jaschke. (2019). Simulated sandwich enzyme‐linked immunosorbent assay for a cost‐effective investigation of natural and engineered cellular signaling pathways. Biochemistry and Molecular Biology Education. 18 September 2019. DOI: https://doi.org/10.1002/bmb.21304.
Abstract PDF
Abstract PDF
Russel M. Vincent, Pandelitsa F. Yiasemides, Paul R Jaschke. (2019). An orthogonal amber initiator tRNA functions similarly across diverse Escherichia coli laboratory strains.
ScienceMatters. 1 May 2019. DOI: 10.19185/matters.201904000009
Abstract PDF
ScienceMatters. 1 May 2019. DOI: 10.19185/matters.201904000009
Abstract PDF
Paul R Jaschke, Gabrielle A Dotson, Kay Hung, Diane Liu, Drew Endy. (2018). Definitive demonstration by synthesis of genome annotation completeness. bioRxiv. 455428. https://doi.org/10.1101/455428
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NAR BREAKTHROUGH ARTICLE
Ariel Hecht*, Jeff Glasgow*, Paul R. Jaschke*, Lukmaan Bawazer*, Matthew S. Munson, Jennifer Cochran, Drew Endy, Marc Salit. (2016). Measurements of translation initiation from all 64 codons in E. coli. Nucleic Acids Research. (2017) 45 (7): 3615-3626. DOI: 10.1093/nar/gkx070 *Authors contributed equally to the paper as first authors. |
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Figure 2. Translation initiation from all 64 codons. Normalized per-cell fluorescence measured from three replicate cultures, grown in LB and resuspended in PBS before measurement, with each of the 64 codons as the start codon in the GFP coding sequence. Shapes represent the replicate plate number, and filled shapes represent GFP expression significantly greater (adjusted P < 0.05) than the non-expressing control (Control) as determined by Dunnett’s test.
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Ariel Hecht*, Jeff Glasgow*, Paul R. Jaschke*, Lukmaan Bawazer*, Matthew S. Munson, Jennifer Cochran, Drew Endy, Marc Salit. (2016). Measurements of translation initiation from all 64 codons in E. coli. bioRxiv. Pre-print.
*Authors contributed equally to this work Link |
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Hessel A, Quinn J, Jaschke PR. Sequence of Synthetic øX174 Bacteriophage. Museum of Modern Art (MoMA). Accessioned Item. New York, USA (Invited Exhibit)
Hessel A, Quinn J, Jaschke PR. Synthetic øX174 Bacteriophage. Design and Violence Exhibit. Museum of Modern Art (MoMA). New York, USA (Invited Exhibit).
Link
Link
Jaschke PR, Ju Lu, Widya Mulyasasmita, and Luke J. Lee. (2013). Incyte Pharmaceuticals Is Primed For A Run. Seeking Alpha.
Link
Link
Jaschke PR, Lieberman EK, Rodriguez J, Sierra A, Endy D. (2012). A fully decompressed synthetic bacteriophage øX174 genome assembled and archived in yeast. Virology. (Cover).
DOI: 10.1016/j.virol.2012.09.020. Abstract PDF Refactored øX174.1f genome sequence: JX913857 |
Neupane B, Jaschke P, Saer R, Beatty JT, Reppert M, Jankowiak R. (2012). Electron Transfer in Rhodobacter sphaeroides Reaction Centers Containing Zn-Bacteriochlorophylls: A Hole Burning Study. The Journal of Physical Chemistry B. Mar 15; 116(10): 3457-3466.
DOI: 10.1021/jp300304r
Abstract PDF
DOI: 10.1021/jp300304r
Abstract PDF
Jaschke PR, Hardjasa A, Digby E, Hunter CN, Beatty JT. (2011). A bchD (Mg-chelatase) mutant of Rhodobacter sphaeroides synthesizes zinc-bacteriochlorophyll through a novel zinc-containing intermediates. The Journal of Biological Chemistry. Jun 10;286(23):20313-22.
DOI: 10.1074/jbc.M110.212605
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DOI: 10.1074/jbc.M110.212605
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Jaschke PR, Saer RG, Noll S, Beatty JT. (2011). Modification of the genome of Rhodobacter sphaeroides and construction of synthetic operons. Methods in Enzymology. 497:519-38.
DOI: 10.1016/B978-0-12-385075-1.00023-8
Abstract PDF
DOI: 10.1016/B978-0-12-385075-1.00023-8
Abstract PDF
Jaschke PR. (2010). Discovery and characterization of a new zinc-bacteriochlorophyll biosynthetic pathway and photosystem in a magnesium-chelatase mutant. PhD Thesis. University of British Columbia. Abstract PDF
Lin S, Jaschke PR, Wang H, Paddock M, Tufts A, Allen JP, Rosell FI, Mauk GA, Woodbury NW, Beatty JT. (2009). Electron transfer in the Rhodobacter sphaeroides reaction center assembled with zinc bacteriochlorophyll. Proceedings of the National Academy of Sciences of the USA. 106(21): 8537-42.
DOI: 10.1073/pnas.0812719106 Abstract PDF |
Jaschke PR, LeBlanc HN, Lang AS, Beatty JT. (2008). The PucC protein of Rhodobacter capsulatus mitigates an inhibitory effect of light-harvesting 2 alpha and beta proteins on light-harvesting complex 1. Photosynthesis Research. 95(2-3): 279-84.
DOI: 10.1007/s11120-007-9258-x
Abstract PDF
DOI: 10.1007/s11120-007-9258-x
Abstract PDF