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Paul Jaschke
Lecturer (Assistant Professor) in Synthetic Biology
Department of Chemistry and Biomolecular Sciences, Macquarie University

Education
B.Sc. (Honours) Biochemistry, The University of Alberta
Ph.D. Microbiology & Immunology, The University of British Columbia
Postdoc Bioengineering, Stanford University
CV
ORCiD: orcid.org/0000-0003-2359-1301
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My Other Profiles
Research Gate Profile
LinkedIn Profile
Academia.edu Profile
Twitter
Mendeley Profile
Google Scholar Profile
OpenWetWare
My Macquarie Page

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***Your name here***

PhD Project in Bacteriophage Synthetic Biology (available to start in 2020 or 2021)
I am seeking an innovative and highly motivated PhD student candidate to work within a multidisciplinary team on a cutting-edge NHMRC-funded project at the intersection of synthetic biology and phage therapy:  engineering new phage to address antibiotic resistant uropathogenic E. coli infections.

To be eligible to apply the candidate must:

1. Be considered a Domestic student (Australian citizen or permanent resident)

2. Completed either a:
(a) Master of Research (MRes) with a grade of at least a Distinction level (75% or greater in second year; or
(b) Master of Philosophy; or
(c) Two-year Masters degree with a major research component at Distinction level (75% or greater).

We encourage candidates of all backgrounds to apply.

If you are interested please email a copy of your CV to paul.jaschke@mq.edu.au and we can discuss further.

Are you curious about synthetic biology and pushing the limits of genetic system design? 

​I am looking for both undergraduate and graduate level (HDR) students  to join the lab in 2021.  Masters of Research and PhD scholarships may be available for candidates who have published in international journals and received awards. If you are interested please forward a copy of your CV to paul.jaschke@mq.edu.au

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Current Lab Members

Higher-Degree Research Students

Pamela Tsoumbris - MRes Student (July 2020 - Current)
B.Sc. in Molecular Molecular Biology and Genetics, The University of Sydney (2018)

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Dominic Scopelliti - PhD Student (Feb 2020 - Current)
B.Sc. in Molecular Sciences, Macquarie University (2018)
Masters of Research, Molecular Sciences, Macquarie University (2019)

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Ellina Trofimova - Masters of Research Student (Jan 2020 - Current)
B.Sc. in Molecular Sciences, Macquarie University (2018)

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Andy Hutvagner - PhD Student (Jan 2019 - Current)
​B.Sc. in Molecular Sciences, Macquarie University (2017)
​Masters of Research, Molecular Sciences, Macquarie University (2019)

Project
I’m am currently working on engineering new ways to initiate and control the translation of desirable proteins in E.coli. Ultimately, I aim for this to contribute new mechanisms towards the development of an orthogonal central dogma: a new and improved system which scientists can utilise to enhance their designs in synthetic biology. 

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Russel Vincent - PhD student (Jan 2018 - Current)
B.Sc. (Honors) in Microbiology,  St. Xavier’s College, Kolkata (India) (2016)
Masters of Research, Molecular Sciences, Macquarie University (2018)
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Project
My work is focusing on the intersection of protein translation and start codons. Recently it was discovered that many previously unrecognised codons are able to initiate translation in E. coli and I am characterising this phenomena more fully while looking at potential applications in synthetic biology.

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Bradley Wright - PhD student (Sept 2016 - Current)
B.Sc, University of Technology Sydney (2013)
Masters of Research, Molecular Sciences, Macquarie University (2015)
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​Project: I am currently interested in applying proteomics to the study of engineered biological systems. I hope to gain insight to how these systems operate at the proteome level as well as guide the design process that will ultimately lead us to better understanding how we can produce more efficient designs.

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Dominic Logel - PhD student (July 2016 - Current)
B.Sc, Biomolecular Sciences (Macquarie University)
M.Res, Structural Biology (Macquarie University)

​Project
My project is attempting to determine the role of synthetic regulation and gene essentiality on a whole viral genome by deep characterisation on the changes that ensue from each genomic design synthesised. By addressing these parameters, genomic design criteria can be elucidated so as to catalogue what changes can be made to a whole genome, whilst maintaining or improving organism survival and replication. The results from this project will also determine the degree from which an organisms regulation and genome organisation can be divorced from nature so as to synthesise increasingly rational organisms.

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Graduate/Undergraduate Students

Ellina Trofimova
• FOSC806 Masters of Science intern working on engineering phage

Alumni

Macquarie University

Amy Callaghan
• Molecular Sciences Department Summer Vacation Scholarship (2019)

Ellina Trofimova
• Summer volunteer working on building transcriptional promoter removal webtool (2019)

Karl Myers
• CBMS389 Summer Research Student (2018)

Nicolas Aryanpour
• BIOL860 Biology research experience​ student (2018)

Pandelitsa (Zoe) Yiasemides
• MQ Department of Molecular Sciences Summer Vacation Scholarship Student (2018)

Stanford University

Gabrielle Dotson
• Bioengineering undergrad, Stanford University
• NIH summer intern
• The Bing Stanford in Washington (BSIW) Program 2015/2016

Kay Hung
• Bioengineering undergrad, Stanford University

Erica Lieberman
• Bioengineering undergrad, Stanford University
• The Bing Stanford in Washington (BSIW) Program 2013/2014
• Eligo Bioscience

Diane Liu
• Bioengineering undergrad at Northwestern University, Chicago

Jon Rodriguez
• Chief Scientist/Founder of Epiphany Eyewear/Vergence Labs acquired by Snapchat 

Adrian Sierra
• Computer Scientist working for Adobe Systems, San Jose

The University of British Columbia

Amelia Hardjasa
• Data Analyst at EnerNOC, Vancouver

Tobie Patterson
• Analyst, Public Health Initiatives at Fraser Health Authority,

Elizabeth Digby
• Medical School at the University of Calgary

Connie Lee
• Physiotherapy in Victoria