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Dr. Paul Jaschke
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Current Lab Members
Higher-Degree Research Students
Sanila Asad - MRes Student (Aug 2022 - Current)
Graduate Diploma, Infection and Immunity, The University of Sydney (2019)
B.Sc. (honours) in Biotechnology, Forman Christian College (2014)
Project: Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.
Graduate Diploma, Infection and Immunity, The University of Sydney (2019)
B.Sc. (honours) in Biotechnology, Forman Christian College (2014)
Project: Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.
Hannah Zhu - PhD Student (May 2021 - Current)
Masters of Research, Molecular Sciences, Macquarie University (2020)
B.Sc. in Medical Sciences, Macquarie University (2018)
Project: My project is focusing on establishing a high-throughput synthetic biology pipeline for the rational design and synthesis of novel phages to be used as therapeutic treatment of antibiotic resistant pathogens. Specifically, I am targeting multidrug resistant uropathogenic E. coli (UPEC) that is a common cause of acute, chronic, and recurrent urinary tract infections. I aim for generating a diverse library of UPEC-targeting phages with improved performance and efficacy, using the proposed phage engineering pipeline.
Masters of Research, Molecular Sciences, Macquarie University (2020)
B.Sc. in Medical Sciences, Macquarie University (2018)
Project: My project is focusing on establishing a high-throughput synthetic biology pipeline for the rational design and synthesis of novel phages to be used as therapeutic treatment of antibiotic resistant pathogens. Specifically, I am targeting multidrug resistant uropathogenic E. coli (UPEC) that is a common cause of acute, chronic, and recurrent urinary tract infections. I aim for generating a diverse library of UPEC-targeting phages with improved performance and efficacy, using the proposed phage engineering pipeline.
Pamela Tsoumbris - Ph.D. Student (Oct 2021 - Current)
B.Sc. in Molecular Molecular Biology and Genetics, The University of Sydney (2018)
MRes in Molecular Sciences, Macquarie University (2021)
Project: I am currently interested in harnessing synthetic biology to engineer bacteriophage to become more efficient at lysing atypical bacterial infections. In doing so, I hope to broaden our understanding of phage interactions with bacterial hosts – specifically in the context of uropathogenic E. coli.
B.Sc. in Molecular Molecular Biology and Genetics, The University of Sydney (2018)
MRes in Molecular Sciences, Macquarie University (2021)
Project: I am currently interested in harnessing synthetic biology to engineer bacteriophage to become more efficient at lysing atypical bacterial infections. In doing so, I hope to broaden our understanding of phage interactions with bacterial hosts – specifically in the context of uropathogenic E. coli.
Dominic Scopelliti - PhD Student (Feb 2020 - Current)
BMedScs, Macquarie University (2018)
Masters of Research, Molecular Sciences, Macquarie University (2019)
Project: I am currently interested in utilising mass spectrometry to characterise proteins expressed using an orthogonal translation initiation system in E. coli. It is my goal to improve our understanding of how the use of an orthogonal system may impact protein expression and to explore its potential applications in synthetic biology.
BMedScs, Macquarie University (2018)
Masters of Research, Molecular Sciences, Macquarie University (2019)
Project: I am currently interested in utilising mass spectrometry to characterise proteins expressed using an orthogonal translation initiation system in E. coli. It is my goal to improve our understanding of how the use of an orthogonal system may impact protein expression and to explore its potential applications in synthetic biology.
Ellina Trofimova - Ph.D. Student (Feb 2022 - Current)
MRes in Molecular Sciences, Macquarie University (2021)
MSc in Chemical and Molecular Sciences, Macquarie University (2019)
Project: My project is focused on engineering icosahedral bacteriophages to extend their bacterial host range. Additionally, I use bioinformatics to understand the genetic determinants of phage infection. Altogether, my research is aimed to broaden the fundamental knowledge of the bacteriophage infection process to create more efficient treatments with phage therapy..
MRes in Molecular Sciences, Macquarie University (2021)
MSc in Chemical and Molecular Sciences, Macquarie University (2019)
Project: My project is focused on engineering icosahedral bacteriophages to extend their bacterial host range. Additionally, I use bioinformatics to understand the genetic determinants of phage infection. Altogether, my research is aimed to broaden the fundamental knowledge of the bacteriophage infection process to create more efficient treatments with phage therapy..
Andy Hutvagner - PhD Student (Jan 2019 - Current)
B.Sc. in Molecular Sciences, Macquarie University (2017)
Masters of Research, Molecular Sciences, Macquarie University (2019)
Project
I’m am currently working on engineering new ways to initiate and control the translation of desirable proteins in E.coli. Ultimately, I aim for this to contribute new mechanisms towards the development of an orthogonal central dogma: a new and improved system which scientists can utilise to enhance their designs in synthetic biology.
B.Sc. in Molecular Sciences, Macquarie University (2017)
Masters of Research, Molecular Sciences, Macquarie University (2019)
Project
I’m am currently working on engineering new ways to initiate and control the translation of desirable proteins in E.coli. Ultimately, I aim for this to contribute new mechanisms towards the development of an orthogonal central dogma: a new and improved system which scientists can utilise to enhance their designs in synthetic biology.
Lab Alumni
Macquarie University
Kein Huynh
• Earned Masters of Research degree
Dr. Dominic Y. Logel
• Earned PhD and completed 1 year postdoc
Dr. Russel Vincent
• Postdoctoral Researcher in George Church's lab at Harvard Medical School
Dr. Bradley Wright
• Postdoctoral Researcher in Jin Chen's lab at UT Southwestern Medical Center
Amy Callaghan
• Scientific Officer at Laverty Pathology
Karl Myers
• Legal Intern, Amgen
Nicolas Aryanpour
• PhD student Louvain-la-Neuve, Belgium
Pandelitsa (Zoe) Yiasemides
• Laverty Pathology
• MQ Department of Molecular Sciences Summer Vacation Scholarship Student (2018)
• Earned Masters of Research degree
Dr. Dominic Y. Logel
• Earned PhD and completed 1 year postdoc
Dr. Russel Vincent
• Postdoctoral Researcher in George Church's lab at Harvard Medical School
Dr. Bradley Wright
• Postdoctoral Researcher in Jin Chen's lab at UT Southwestern Medical Center
Amy Callaghan
• Scientific Officer at Laverty Pathology
Karl Myers
• Legal Intern, Amgen
Nicolas Aryanpour
• PhD student Louvain-la-Neuve, Belgium
Pandelitsa (Zoe) Yiasemides
• Laverty Pathology
• MQ Department of Molecular Sciences Summer Vacation Scholarship Student (2018)
Stanford University
Gabrielle Dotson
• Ph.D. Candidate at University of Michigan - Department of Computational Medicine & Bioinformatics
• Bioengineering undergrad, Stanford University
Kay Hung
• General Surgery Resident, Stanford Medicine, Stanford University
• Bioengineering undergrad, Stanford University
Erica Lieberman
• Eligo Bioscience
• Bioengineering undergrad, Stanford University
Diane Liu
• Software Engineering at Gusto
Jon Rodriguez
• Chief Scientist/Founder of Epiphany Eyewear/Vergence Labs acquired by Snapchat
Adrian Sierra
• Computer Scientist working for Adobe Systems, San Jose
• Ph.D. Candidate at University of Michigan - Department of Computational Medicine & Bioinformatics
• Bioengineering undergrad, Stanford University
Kay Hung
• General Surgery Resident, Stanford Medicine, Stanford University
• Bioengineering undergrad, Stanford University
Erica Lieberman
• Eligo Bioscience
• Bioengineering undergrad, Stanford University
Diane Liu
• Software Engineering at Gusto
Jon Rodriguez
• Chief Scientist/Founder of Epiphany Eyewear/Vergence Labs acquired by Snapchat
Adrian Sierra
• Computer Scientist working for Adobe Systems, San Jose
The University of British Columbia
Amelia Hardjasa
• Data Analyst at EnerNOC, Vancouver
Tobie Patterson
• Analyst, Public Health Initiatives at Fraser Health Authority,
Elizabeth Digby
• Medical School at the University of Calgary
Connie Lee
• Physiotherapy in Victoria
• Data Analyst at EnerNOC, Vancouver
Tobie Patterson
• Analyst, Public Health Initiatives at Fraser Health Authority,
Elizabeth Digby
• Medical School at the University of Calgary
Connie Lee
• Physiotherapy in Victoria
