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    • Macquarie University
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Dr. Paul Jaschke
Senior Lecturer (equiv. Associate Professor) in Synthetic Biology
School of Natural Sciences, Macquarie University

Education
Postdoctoral Fellow, Bioengineering, Stanford University (2015)
Ph.D. Microbiology & Immunology, The University of British Columbia (2010)
B.Sc. (Honours) Biochemistry, The University of Alberta (2002)

​CV

ORCiD: orcid.org/0000-0003-2359-1301
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My Other Profiles
Research Gate Profile
LinkedIn Profile
Academia.edu Profile
Twitter
Mendeley Profile
Google Scholar Profile
OpenWetWare

***Your name here***

Are you curious about synthetic biology and pushing the limits of genetic system design? 
​I am always looking for the right graduate level (HDR) students to join the lab.  Masters of Research and PhD scholarships may be available for candidates who have published in international journals and received awards. If you are interested please forward a copy of your CV to paul.jaschke@mq.edu.au

Current Lab Members

Higher-Degree Research Students

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Sanila Asad - MRes Student (Aug 2022 - Current)
Graduate Diploma, Infection and Immunity, The University of Sydney (2019)
B.Sc. (honours) in Biotechnology,
Forman Christian College (2014)

​Project: 
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Hannah Zhu - PhD Student (May 2021 - Current)
Masters of Research, Molecular Sciences, Macquarie University (2020)
B.Sc. in Medical Sciences, Macquarie University (2018)

​Project: 
My project is focusing on establishing a high-throughput synthetic biology pipeline for the rational design and synthesis of novel phages to be used as therapeutic treatment of antibiotic resistant pathogens. Specifically, I am targeting multidrug resistant uropathogenic E. coli (UPEC) that is a common cause of acute, chronic, and recurrent urinary tract infections. I aim for generating a diverse library of UPEC-targeting phages with improved performance and efficacy, using the proposed phage engineering pipeline.

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Pamela Tsoumbris - Ph.D. Student (Oct 2021 - Current)
​B.Sc. in Molecular Molecular Biology and Genetics, The University of Sydney (2018)
MRes in Molecular Sciences, Macquarie University (2021)

Project: I am currently interested in harnessing synthetic biology to engineer bacteriophage to become more efficient at lysing atypical bacterial infections. In doing so, I hope to broaden our understanding of phage interactions with bacterial hosts – specifically in the context of uropathogenic E. coli.​

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Dominic Scopelliti - PhD Student (Feb 2020 - Current)
BMedScs, Macquarie University (2018)
Masters of Research, Molecular Sciences, Macquarie University (2019)

Project
: 
I am currently interested in utilising mass spectrometry to characterise proteins expressed using an orthogonal translation initiation system in E. coli.  It is my goal to improve our understanding of how the use of an orthogonal system may impact protein expression and to explore its potential applications in synthetic biology. 

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Ellina Trofimova - Ph.D. Student (Feb 2022 - Current)
MRes in Molecular Sciences, Macquarie University (2021)
MSc in Chemical and Molecular Sciences, Macquarie University (2019)


Project: My project is focused on engineering icosahedral bacteriophages to extend their bacterial host range. Additionally, I use bioinformatics to understand the genetic determinants of phage infection. Altogether, my research is aimed to broaden the fundamental knowledge of the bacteriophage infection process to create more efficient treatments with phage therapy..​​

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Andy Hutvagner - PhD Student (Jan 2019 - Current)
​B.Sc. in Molecular Sciences, Macquarie University (2017)
​Masters of Research, Molecular Sciences, Macquarie University (2019)


Project
I’m am currently working on engineering new ways to initiate and control the translation of desirable proteins in E.coli. Ultimately, I aim for this to contribute new mechanisms towards the development of an orthogonal central dogma: a new and improved system which scientists can utilise to enhance their designs in synthetic biology. 

Lab Alumni

Macquarie University

Kein Huynh
• Earned Masters of Research degree

Dr. Dominic Y. Logel
• Earned PhD and completed 1 year postdoc

Dr. Russel Vincent
• 
Postdoctoral Researcher in George Church's lab at Harvard Medical School

Dr. Bradley Wright
• 
Postdoctoral Researcher in Jin Chen's lab at UT Southwestern Medical Center

Amy Callaghan
• Scientific Officer at Laverty Pathology

Karl Myers
• Legal Intern, Amgen


Nicolas Aryanpour
• PhD student Louvain-la-Neuve, Belgium

Pandelitsa (Zoe) Yiasemides
• Laverty Pathology
​• MQ Department of Molecular Sciences Summer Vacation Scholarship Student 
(2018)

Stanford University

Gabrielle Dotson
• Ph.D. Candidate at University of Michigan - Department of Computational Medicine & Bioinformatics
• Bioengineering undergrad, Stanford University

Kay Hung
• General Surgery Resident, Stanford Medicine, Stanford University
​• Bioengineering undergrad, Stanford University

Erica Lieberman
• Eligo Bioscience
• Bioengineering undergrad, Stanford University

Diane Liu
• Software Engineering at Gusto

Jon Rodriguez
• Chief Scientist/Founder of Epiphany Eyewear/Vergence Labs acquired by Snapchat 

Adrian Sierra
• Computer Scientist working for Adobe Systems, San Jose

The University of British Columbia

Amelia Hardjasa
• Data Analyst at EnerNOC, Vancouver

Tobie Patterson
• Analyst, Public Health Initiatives at Fraser Health Authority,

Elizabeth Digby
• Medical School at the University of Calgary

Connie Lee
• Physiotherapy in Victoria
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Contact

paul.jaschke@mq.edu.au
+61 2 9850 8295
School of Natural Sciences
Faculty of Science and Engineering
Macquarie University
Sydney, New South Wales
​Australia

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